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If You Have High Pyridoxine In Your Blood, Here’s The Solution

Are you having high pyridoxine in your blood? Pyridoxine, also known as vitamin B6 is water soluble, this means it easily dissolves in water.

Vitamin B6 helps our body make red blood cells, develops the brain, and boosts the immune system to work well.

But having too much pyridoxine in your blood can be harmful to the body if not treated.

In this post, we’ll talk about the causes, symptoms, and how to solve this problem.

What is Hyperpyridoxinemia?

Hyperpyridoxinemia simply means having high levels of pyridoxine in your blood.

When you take high doses of vitamin B6 supplements, it builds up in the body overtime, this is called pyridoxine toxicity.

The normal range for pyridoxine levels is between 5 and 50 nmol/L.

In addition, vitamin B6 toxicity, can occur when levels exceed 1000 nmol/L.

According to the National Institute of Health, the RDA of vitamin B6 for adults is 1.3-1.7 mg per day, and taking more than 100 mg/day causes hyperpyridoxinemia.

Causes of High Pyridoxine Levels

High pyridoxine levels can occur due to a number of factors, this is caused by:

  • Eating foods that is high in vitamin B6
  • Taking too much pyridoxine supplements
  • Interactions with isoniazid and cycloserine
  • Inflammatory bowel disease
  • Leukemia
  • Lymphoma

Symptoms of High Pyridoxine Levels

Although pyridoxine is good for our health, high levels of this vitamin in the blood is not safe. Symptoms include:

  • Tingling
  • Burning in the hands and feet
  • Loss of coordination and balance
  • Increased sensitivity to light
  • Difficulty in walking
  • Nausea and vomiting
  • Skin inflammation
  • Increased liver enzymes
  • Seizures

Diagnosis of High Pyridoxine Levels

Serum vitamin B6 tests should be done to check the amount of pyridoxine in your blood.

Physical examination can also help identify the symptoms, such as skin lesions and nerve damage.

Treatment for High Pyridoxine Levels

If you suspect high pyridoxine levels in your blood, here’s a simple way to treat this:

  • Stop taking pyridoxine supplements
  • Use antihistamines and topical creams to relieve the symptoms

Prevention of High Pyridoxine Levels

Drug interaction: Try to avoid medications that interferes with the absorption of vitamin B6. Examples are seromycin (cycloserine) and epilepsy drugs.

Control your diet: You can change diets by reducing the intake of pyridoxine-rich foods. Make sure you stick to the recommended daily intake for vitamin B6.

Here are the guidelines:

  • Infants 0-6 months: 0.1-0.3 mg/day
  • Infants 7-12 months: 0.3-0.6 mg/day
  • Children 1-3 years: 0.5 mg/day
  • Children 4-8 years: 0.6 mg/day
  • Children 9-13 years: 1.0 mg/day
  • Teens 14-18 years: 1.2-1.3 mg/day
  • Adults 19-50 years: 1.3 mg/day
  • Adults 51+ years: 1.5-1.7 mg/day
  • Pregnant women: 1.9 mg/day
  • Lactating women: 2.0 mg/day

Pregnant and lactating women need significant amounts of vitamin B6 due to the demands of fetal and infant growth.

Conclusion: Are you having high pyridoxine in your blood?

Having too much pyridoxine in your body is a big problem and can cause all sorts of health issues.

But don’t worry. If you get the right diagnosis and treatment, you can control the condition and stop it from creating more problems in the future.

To stay healthy, eat a balanced diet, follow the recommended daily intake allowance, and don’t take too much pyridoxine supplements.

Related: Are you having high riboflavin in your blood? Here’s the solution

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